Search results for "Dry eye disease"
showing 10 items of 11 documents
Use of digital displays and ocular surface alterations
2023
Aunque nuestra comprensión de los efectos del uso de dispositivos electrónicos sobre la superficie ocular ha aumentado considerablemente desde el inicio de siglo, varias preguntas importantes siguen sin respuesta. Asimismo, los avances tecnológicos y la aparición de nuevas formas de dispositivos digitales hacen necesaria una investigación continua. Esta tesis doctoral presenta un total de 12 estudios independientes los cuales constituyen los pilares de este trabajo (Capítulos 4-15). En primer lugar, el Capítulo 4 tuvo como objetivo evaluar la asociación entre los factores de riesgo de la enfermedad de ojo seco (EOS) y el síndrome visual informático (SVI). Se llevó a cabo una encuesta online…
Non-invassive assessment of the tear film and the ocular surface: Effect of contact lenses
2022
El diagnóstico y tratamiento del síndrome del ojo seco es un reto debido al carácter multifactorial de la enfermedad y la falta de un test clínico “gold standard”. Además, la falta de correlación entre los signos y síntomas de la enfermedad del ojo seco, la falta de correlación entre métricas, su baja repetibilidad, su carácter invasivo y su relativa objetividad dificulta el estudio de la película lagrimal y el diagnóstico de la enfermedad del ojo seco. En el Capítulo 1 del presente trabajo se describen las características principales de la película lagrimal y la enfermedad del ojo seco, y se realiza una revisión bibliográfica sobre técnicas no invasivas de análisis de la película lagrimal …
TFOS DEWS II Sex, Gender, and Hormones Report
2017
One of the most compelling features of dry eye disease (DED) is that it occurs more frequently in women than men. In fact, the female sex is a significant risk factor for the development of DED. This sex-related difference in DED prevalence is attributed in large part to the effects of sex steroids (e.g. androgens, estrogens), hypothalamic-pituitary hormones, glucocorticoids, insulin, insulin-like growth factor 1 and thyroid hormones, as well as to the sex chromosome complement, sex-specific autosomal factors and epigenetics (e.g. microRNAs). In addition to sex, gender also appears to be a risk factor for DED. âGenderâ and âsexâ are words that are often used interchangeably, but the…
Chambered warm moist air eyelid warming devices – a review
2021
Background Eyelid warming is an important treatment for meibomian gland dysfunction (MGD). Specialized chambered devices, using warm moist air have been developed. Purpose To critically evaluate the literature on the safety and efficacy of chambered warm moist air devices in MGD treatment and pinpoint areas of future research. Methods PubMed and Embase were searched on 06 June 2021. The search term was ‘(warm OR heat OR steam OR goggle OR spectacle OR moist air) AND (meibomian OR MGD OR blepharitis OR eyelid OR dry eye OR DED)’. All relevant articles with available English full text were included. Results Eighteen articles assessing the application of chambered warm moist air eyelid warming…
The effects of microwave radiation generated by mobile phones on the tear film
2021
Abstract Electromagnetic radiation (ER) emitted by mobile phones and other modern devices has potentially harmful effects on ocular tissue. Their effects on the eye surface and tear film are little known so far. The aim of this paper was to investigate the effects of ER emitted by the phone mobile on the tear film. For this study, we selected a total of 50 subjects, young, healthy, without chronic treatment, who are not contact lens wearers and who have no history of ophthalmic surgery. Schirmer I test, tear pH and tear ferning test (TFT) were performed on all subjects before (“-pre”) being exposed to ER emitted by the mobile phone and after (“-post”) exposure for 5 minutes, the pH and TFT …
Video display terminal use and dry eye: preventive measures and future perspectives
2022
Background: Dry eye disease (DED) is a common cause of ocular pain and discomfort. Dry eye disease (DED) stems from a loss-of-tear film homeostasis and is frequently seen in video display terminal (VDT) users. Video display terminal (VDT) use reduces blink rates and increases incomplete blinks, leading to tear film instability and ocular inflammation, promoting DED. Purpose: To assess and evaluate the methods for preventing VDT-associated DED and ocular discomfort. Methods: Studies were found using PubMed and Embase with the search terms: (digital visual terminal* OR computer use OR screen use OR smartphone OR display OR visual display terminal* OR computer vision syndrome OR tablet OR phon…
Silto acu komprešu ietekme uz acs asaru slāņa īpašībām
2021
Pētījuma mērķis bija novērtēt silto komprešu terapijas efektivitāti uz asaru slāņa īpašībām pacientiem ar sausas acs subjektīvo simptomātiku. 18 pētījuma dalībniekieki, lietojot TheraPearl acu maskas divas reizes dienā no rīta un vakarā pa 5 vai 10 minūtēm, veica silto komprešu terapiju 14 dienu periodā. Diagnostikie mērījumi pirms terapijas, pēc terapijas un trīs nedēļas pēc terapijas beigām tika veikti asaru slāņa īpašību novērtēšanai. Dalībnieki pēc terapijas uzrādīja ievērojamu OSDI un DEQ-5 anketu rezultāta uzlabošanos un uzlabojums saglabājās arī trīs nedēļas pēc terapijas beigām. Pēc terapijas netika novērots statiski būtisks uzlabojums neinvazīvajā asaru slāņa plīšanas laikā (NIBUT).
Topical glaucoma medications – Clinical implications for the ocular surface
2022
Glaucoma is a leading cause of irreversible blindness. The use of topical eye drops to reduce intraocular pressure remains the mainstay treatment. These eye drops frequently contain preservatives designed to ensure sterility of the compound. A growing number of clinical and experimental studies report the detrimental effects of not only these preservatives but also the active pharmaceutical compounds on the ocular surface, with resultant tear film instability and dry eye disease. Herein, we critically appraise the published literature exploring the effects of preservatives and pharmaceutical compounds on the ocular surface. publishedVersion
Hot towels
2023
Background Meibomian gland dysfunction (MGD) reduces quality-of-life and hinders work productivity of millions of patients, with high direct and indirect societal costs. Thickened meibum obstructs the glands and disrupts ocular surface health. Heating the eyelids to soften and express meibum from the glands can be beneficial. The most accessible method for eyelid warming uses heated, wet towels. However, the efficacy of this treatment is reliant on the methodology, and evidence-based best-practice recommendations are needed. Purpose To evaluate the literature on hot towels in MGD treatment and recommend a best-practice protocol for future research and patient treatment. Methods Studies were…
Approche nutritionnelle de la thérapie du syndrome de l'œil sec : prévention par les acides gras polyinsaturés
2008
Dry eye disease affects 15% of the population over the age of 65. It is characterized mainly by inflammation of the ocular surface (tear film, conjunctiva and cornea) which represents a relevant target for therapeutic strategies. The side effects and long-term intolerance of anti-inflammatory drugs give rise to an increasing interest for dietary components exhibiting anti-inflammatory properties, such as polyunsaturated fatty acids (PUFAs). In these studies, we developed a scopolamine-induced dry eye model in the rat that mimics changes occurring in Humans suffering from moderate dry eye. We described the time course of clinical signs, inflammation and mucin production loss. We investigated…